The inherited ailment characterized by recurrent bouts of fever,
inflammation, and pain in the chest, muscles and joints is known as
familial Mediterranean fever. This rare disorder can be diagnosed early
in life however, first signs of recurrent attacks usually occurs in the
later teenage years. This disease generally effects those people
originating within Armenia, Turkey and other surrounding Mediterranean
regions. That being said, it can still affect those of different
nationalities. While severity ranges from patient to patient, these
recurrent episodes can last anywhere between a few hours up to 3 days.
Treating FMF
Colchicine
is the drug used to treat familial Mediterranean fever. It has been
proven to be the most effective form of treatment, helping to
dramatically reduce episodic attacks and further complications for the
majority of FMF sufferers. Without this prescribed drug, amyloidosis,
better known as the build of amyloid protein, can occur throughout the
organs and tissues of the body, resulting in the potential for kidney
failure. It is best for FMF patients to use colchicine under the
discretion of their physicians approval.
Here are some other names individuals use for Familial Mediterranean Fever:
FMF
Periodic Peritonitis
MEF
Reimann Periodic Disease
Wolff Periodic Disease
Recurrent Polyserositis
Mediterranean Fever, Familial
Siegal-Cattan-Mamou Disease
Periodic Disease
The Gene Associated With Periodic Peritonitis
The
MEFV gene helps regulate inflammation and produces the pyrin protein
found in white blood cells. Mutations of this gene cause FMF by reducing
the amount of protein pyrin produced, which interferes with the
regulation of inflammation and signaling white blood cells to injury
sites. Symptoms and attacks including muscle, joint, abdominal pain and
fever are a result of prolonged inflammatory response.
FMF Inheritance
Both
gene copies in cells will have mutations in order for someone to be
diagnosed with familial Mediterranean fever. In other words, while both
parents of a child obtaining an autosomal recessive condition carry a
copy of the gene mutation without showing any symptoms of the condition,
it is typically inherited in an autosomal recessive form. There are
other cases where this condition can be inherited in various forms
including an autosomal recessive inheritance and an autosomal dominant
pattern.
A healthy body can fight off cancer cells and when the
body can control or manage inflammation or is capable of resisting
pathogens, diseases and cancers can be avoided. If you feel your
suffering from inflammation, make sure to consult your nearest physician
to learn more about your current condition.
Article Source: http://EzineArticles.com/7245306
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