PET/CT Scan Challenge Of Pleural Effusion Treatment For Mesothelioma Patients

Early detection of the fatal and incurable mesothelioma and the subsequent provision of radiation, surgical and palliative asbestosis treatments are known to help a patient to have the best possible chance to extend and improve the quality of life remaining.

Crucial to the process is the use of body scanning technologies, ranging from X-rays, MRI (Magnetic Resonance Imaging), CT (computed tomography) or CAT scans, and the more advanced PET/CT (positron emission tomography and computerized tomography).

The long gestation period of up to 50 years from first asbestos exposure and inhaling of the fibre dust to the appearance of asbestosis symptoms can often mean that a diffuse malignant mesothelioma has reached an advanced stage and spread to other organ tissues.

While X-rays of chest or abdomen can detect fluid build-up, masses, or signs of non-cancerous pleural disease, evidence of diffuse cancerous growths by radiology will only show as a shadow formed by a single tumour, as with peritoneal mesothelioma. Similarly, despite MRI supplying a highly detailed image of the interior body and can determine the severity of a tumour, this type of scan is still unable to clearly indicate a cancerous growth.

CT scans produce images, which provide a cross section examination of layers of the body to more easily reveal abnormalities at a given depth within the body and can also accurately diagnose lung cancer sooner than chest x-rays, leading to an increased survival rate by up to 20 per cent. However, while CT scans are able to define pleural effusion, pleural thickening, pleural calcification or possible chest wall invasion, they cannot differentiate between benign or malignant mesothelioma.

Mesothelioma patients who suffer painful breathing caused by pleural effusions - the build-up of fluid across the lung linings in response to the spread of mesothelioma tumours - can undergo a procedure for the draining of the fluid and replacing the space with medical talc.

New medical research has found that the fluid draining process may interfere with the PET/CT monitoring, which also involves injecting the patient with a radioactive tracer and the level of absorption by cancer cells subsequently measured by the scan, once after 14 days and then again after 125 days.

Article Source: http://EzineArticles.com/7215061


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Non-Small Cell Lung Cancer - (Stages 0-4)

After non-small cell lung cancer (NSCLC) has been diagnosed in a patient it is given what is called a "stage." This describes both the size of the tumor, and to what extent the tumor has spread within the body. Once diagnosed, a more accurate prognosis (life expectancy) of a patient can be given. There are five main stages of NSCLC (0, 1, 2, 3, 4). Each of these stages is further divided into more specific sub-stages.

(Stages 0-4)

- 0 The cancer has not spread past the inner lining of the lungs; also known as carcinoma in situ (CIS).
- 1 The cancer is localized within the lungs but has not yet spread to the lymph nodes.
- 1A (the tumor is 3 cm or less in diameter).
- 1B (the tumor is greater than 3 cm in diameter).
- 2 The cancer has either spread outside the lungs to the nearby lymph nodes, or has NOT yet spread to the lymph nodes, but is localized in a certain area of the main bronchus (tubes that allow air to pass between the trachea and the lungs). The tumor may also be located in an area where it has invaded the lining of the lungs, or the wall of the chest.
- 2A (the tumor is 3 cm or less and has spread to the lymph nodes).
- 2B (the tumor is greater that 3 cm and has spread to the lymph nodes. It may also be present in the main bronchus region, has invaded the lining of the lungs, or wall of the chest.
- 3 The cancer has spread to the nearby tissue of the lungs.
- 3A (the tumor is lager in size and has spread to the lymph nodes. At this stage multi-tumors of any size may have spread away from the main tumor area).
- 3B (tumors of any size that have spread to distant lymph nodes and have invaded other organs such as the esophagus, the heart, or tumors with malignant pleural effusion [an abnormal amount of fluid in the space between the tissue that lines the inside of the lungs]).
- 4 The cancer has reached its most dangerous stage by having spread to other organs of the body, including another lobe of the lung.

Doctors may often describe NSCLC with a system called TNM. This system is used to further classify lung cancer within its sub-stages. Each letter stands for a different degree (stage) of the disease.

T - (the size of the tumor).
N - (indicates which lymph nodes have been invaded).
M - (defines whether the cancer has metastasized).

Article Source: http://EzineArticles.com/7215023


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All About Asbestos Cancer (Mesothelioma): Types, Symptoms and Compensation Claims

Of the many injuries and work related diseases, mesothelioma is perhaps the one that draws much attention. Every other day a case is reported or a compensation claim is filed. Mesothelioma is a cancer that is almost always caused by earlier exposure to asbestos, approximately in ninety percent of cases.

People normally working in industries where asbestos was used extensively, such as construction work, plumbing, ship yards, old houses and at power stations, were more likely to have been exposed to breathing in asbestos fibrous materials often over a period of years and thus are more likely to suffer from either asbestosis or mesothelioma among others.

In the United Kingdom alone almost 2300 people a year are diagnosed with mesothelioma. At least 3,500 people in Great Britain die every year from asbestos related lung cancer and mesothelioma as a result of past exposure to asbestos fibers.

Types of Mesothelioma

Mesothelioma is a cancerous disease that affects the Mesothelium, which is a thin membrane that covers the lungs or the lining of the abdomen. There are two main types of mesothelioma.

1. Peritoneal (if present in abdomen)

2. Pleural (if present in the chest wall)

Pleural Mesothelioma is more common than peritoneal mesothelioma. Asbestos exposure is the primary cause of mesothelioma. Asbestos fibers are microscopic and once swallowed or breathed in tend to stay in human body. With time they undergo changes and start damaging the body. Thus mesothelioma does not appear suddenly but takes several years before the symptoms start becoming evident.

Mesothelioma is often confused with asbestosis. Asbestosis is also a disease of the lungs that is caused by again the presence of deadly asbestos fibres but it is not cancerous and thus can be treated more effectively if diagnosed at an early stage.

Article Source: http://EzineArticles.com/7295996


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Adenocarcinoma Lung Cancer

Glandular tissue cancer is a type of adencarcinoma, and can affect different parts of the body. Such affected regions in the body include the stomach, the breasts, the colon, cervix, prostate and pancreas just to name a few. One particularly common type of glandular cancer is adenocarcinoma of the lung.

Adenoid cystic carcinoma of the lung is responsible for approximately 40 to 50 percent of diagnosed lung cancers each year. It is a form of non-small cell lung cancers, which accounts for close to 80% of all lung cancers. Detecting such illnesses early on in its journey will definitely increase survival rates in addition to helping alleviate many its side effects. Nevertheless, adenoid cystic carcinoma may not be easily visible during its early stages.

Its origin is typically found surrounding parts of the lungs and is often found in women, even in non-smokers. One of its subtypes known as BAC or bronchioloalveolar carcinoma is found in many non-smoking women. The majority of patients tend to be of Asian decent, and most sufferers are usually under the age of 45. Lung cancer in general is continuing to increase over the years, perhaps due to the increasing amount of smokers across the globe. There have been many suggestions as to the increase in cancer numbers. One being the addition of cigarette filters which have demonstrated to potentially allow even more smoke to be inhaled deeper in the lungs, thus triggering adenoid cystic carcinoma.

Even though early symptoms, for example chest pain or fatigue, tend to be overlooked, there have been some well-known symptoms associated with ACC. Since this form of cancer is prone to spreading from the outer lung, symptoms including coughing up blood and a chronic chough are generally seen. It's imperative to consult your doctor if you have been experiencing any of these signs.

Obviously daily life choices including diet, alcohol consumption, tobacco smoking known as the main cause, and other environmental factors will make you more or less susceptible to adenocarcinoma cancer. Unfortunately adenoid cystic carcinoma of the lungs have affected non-smokers, most commonly caused by radon exposure in the home. While the severity of this cancer varies significantly depending on the affected organ or glandular tissue, there are a few common symptoms. Anything from fatigue, unexplained weight loss or bleeding can all occur, regardless of the organ affected. Because lung adenocarcinoma is a multi-factorial illness, many factors may be the cause of such a serious condition.

Article Source: http://EzineArticles.com/7310833


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